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Department of Surgery Department of Surgery

Lymphatic Exosomes in Health and Disease Network

About the Lymphatic Exosomes in Health and Disease Network

The Lymphatic Exosomes in Health and Disease (LEHD) Network is a multidisciplinary partnership composed of expertise in exosome biogenesis, immunology cross-talk, vesicle flow cytometry, animal models, and clinical samples. We are particularly focused on the exosomes released into mesenteric lymphatics and their biological function in trauma/hemorrhagic shock and in experimental models of colitis/inflammatory bowel disease.


Investigators

Brian Eliceiri, PhD - UC San Diego
Andrew Baird, PhD - UC San Diego
Todd Costantini, MD - UC San Diego
John Nolan, PhD - CellArcus Technologies
Sarah Blair, MD - UC San Diego
Sandip Patel, MD - UC San Diego
Phillip Stahl, PhD - Washington University in St. Louis


Journal Club

Exosomes: Looking back three decades and into the future

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling

Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer

Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity